The word apallotrioo refers to alienation. In conjunction with another word, it is rendered as “be alienated,” and by itself as “be alien. All of the scriptural uses are in Paul, and he uses to describe the condition of those who are strangers to God.
“And you, that were sometime alienated and enemies in your mind by wicked works, yet now hath he reconciled” (Col. 1:21). “Having the understanding darkened, being alienated from the life of God through the ignorance that is in them, because of the blindness of their heart” (Eph. 4:18). “That at that time ye were without Christ, being aliens from the commonwealth of Israel, and strangers from the covenants of promise, having no hope, and without God in the world” (Eph. 2:12).
By its very nature, sin separates and divides. And this is why the ultimate result of sin is ultimate alienation — outer darkness.